Albendazole efficacy hinges on dosing with fat, repeating therapy for certain parasites, and monitoring hepatic and hematologic parameters during prolonged courses.
Albendazole exposure rises two- to five-fold when taken with a fatty meal (e.g., whole milk, avocado toast). Counsel families to schedule doses with substantial snacks to maximize cure rates.
Pinworm, giardia, and hookworm regimens often require a second dose at 14 days; book the follow-up or reminder during the initial encounter to prevent reinfection.
For hydatid disease or neurocysticercosis (cycles of 28 days on/14 days off), check AST/ALT and CBC every two weeks to catch hepatotoxicity or leukopenia early.
For enterobiasis, treat all close contacts simultaneously and emphasize hand hygiene, morning bathing, and hot-water laundering to break the transmission cycle.