Understanding when cefdinir should not be used is essential for your child's safety. Most importantly, avoid this medication if your child has had serious allergic reactions to cephalosporin antibiotics or severe immediate reactions to penicillin.
Cefdinir contraindications include absolute restrictions (cephalosporin allergies, severe immediate penicillin reactions) and relative cautions (severe renal impairment, C. diff history). Key drug interactions involve iron supplements and antacids that can significantly reduce effectiveness.
Any history of immediate hypersensitivity reactions to cefdinir or other cephalosporin antibiotics
History of immediate anaphylactic reaction to penicillin antibiotics within 1 hour of administration
This medication is generally considered safe during pregnancy and breastfeeding when used as directed. However, if you're pregnant or breastfeeding and need to give this medication to your child, it's always a good idea to discuss this with your healthcare provider to ensure it's the best choice for your specific situation.
Specific drugs: See description
Effect: Up to 80% reduction in antibiotic levels
How it happens: Iron chelation dramatically reduces cefdinir absorption
Management: Separate by at least 2 hours
Specific drugs: See description
Effect: Reduced antibiotic effectiveness
How it happens: Metal cations bind to cefdinir reducing absorption
Management: Give cefdinir 2 hours before or 4 hours after antacids
Specific drugs: See description
Effect: Increased cefdinir levels and prolonged half-life
How it happens: Blocks renal tubular secretion of cefdinir
Management: Monitor for increased side effects
Specific drugs: See description
Effect: Theoretical reduced contraceptive efficacy
How it happens: Possible disruption of enterohepatic circulation
Management: Consider backup contraception during treatment
No information available
No information available
Frequency
Continuous during first dose, then daily
Frequency
Daily monitoring
Frequency
Monitor symptoms, labs if indicated
Frequency
Monitor response to therapy