Contraindications

• Known hypersensitivity to cefpodoxime, other cephalosporins, or any component of the formulation

Use With Caution

• History of immediate, severe beta‑lactam allergy (e.g., anaphylaxis) — avoid cephalosporins or use only with specialist guidance
• Non‑severe penicillin allergy — cross‑reactivity is low but assess carefully
• Renal impairment — may require dose adjustment and clinical monitoring

Pregnancy & Lactation

Cephalosporins are generally considered compatible with pregnancy and breastfeeding; individualize with clinician oversight.