Primary FDA-Approved Indications
Ideal for otitis media, sinusitis, and gram-negative infections requiring once-daily dosing when adherence is a concern.
Acute otitis media
FDA ApprovedChildren ≥6 monthsModerate
Reserve for children who cannot tolerate amoxicillin-based therapy or have beta-lactamase risk.
Acute bacterial sinusitis
FDA ApprovedChildren and adolescentsModerate
Ensure criteria for bacterial sinusitis met before prescribing.
Prophylaxis/treatment of gram-negative infections in penicillin-allergic patients
FDA ApprovedSpecialist-directed
Use only under infectious disease guidance (e.g., complicated UTIs).