Guidance for safe chlorpheniramine use (with or without dextromethorphan) in pediatrics.
Clinician-directed ages ≥2 years
Commonly 2 mg/5 mL
Typically ≥6 years
Confirm if product also contains dextromethorphan or other ingredients.
Ensures even distribution.
Use the Children’s Hospital Colorado weight table or the prescriber’s instructions.
Method: Oral syringe inside cheek
Positioning: Seated upright on caregiver lap
Method: Measured tablet or syrup
Positioning: Upright, calm environment
Consider calling your pediatrician if this issue persists
Consider calling your pediatrician if this issue persists
Temperature: 20–25°C (68–77°F)
Stability: Follow manufacturer expiration date
The OTC label for many combos begins at ≥12 years; any younger use is off-label and requires clinician oversight.
Pair dosing discussions with education on saline, humidifiers, and honey (≥1 year) to reinforce supportive care.
You are providing the best care for your child. Follow your healthcare provider's guidance.