Sedation, dry mouth, and slowed reaction time are common. Rarely, paradoxical agitation or hallucinations can occur, especially with higher doses or in younger children.
Monitor closely during the first days of therapy, adjust timing to bedtime, and stop immediately for severe behavioral or cardiovascular symptoms.
2 documented effects
Not specified
Move doses to evening/bedtime; avoid other sedatives; monitor school performance
Monitor for symptom escalation or new adverse effects.
Not specified
Stop the medicine and seek urgent care
Monitor for symptom escalation or new adverse effects.
2 documented effects
Not specified
Offer water, use humidifier, encourage saline spray
Monitor for symptom escalation or new adverse effects.
Not specified
Stop medication and evaluate, especially in adolescents with bladder issues
Monitor for symptom escalation or new adverse effects.
1 documented effect
Not specified
Give with light snack; monitor hydration
Monitor for symptom escalation or new adverse effects.
For babies taking Chlorpheniramine, watch for signs of side effects. This medication is generally well-tolerated in infants when used as directed.
This medicine might make your child very sleepy or cranky.
It can make you tired; tell us if you feel dizzy or your heart is racing.
Don’t drive or play sports until you know how sleepy it makes you; call if you feel agitated or have vision changes.
A: Use bedtime-only dosing or stop the medicine and switch to a non-sedating antihistamine.
When to validate: Contact clinician if daytime functioning is impaired.
A: Stop the medicine immediately and seek medical advice—this can be a sign to avoid the drug.
When to validate: Urgent evaluation if symptoms persist or worsen.
Guide whether to continue, adjust, or stop therapy based on sedation and behavioral effects.
Parent and clinician concerns about Chlorpheniramine