Review GI history, allergy, and hepatic status before prescribing.
Absolute: hypersensitivity to clindamycin/lincomycin. Relative: prior severe antibiotic‑associated colitis, significant GI disease, severe hepatic/renal impairment, and concurrent agents raising C. difficile risk.
Use alternative if feasible; counsel and monitor closely
Discuss with clinician; consider risks/benefits.