Protein synthesis inhibition at the 50S ribosome reduces bacterial toxin production and growth.
Clindamycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, blocking peptide chain elongation. It is bacteriostatic against most susceptible organisms but can be bactericidal at higher concentrations.
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Liquid formulation preferred for accuracy
Use palmitate suspension to achieve precise dosing
Consider clindamycin for toxin suppression in necrotizing infections (specialist care)