Indomethacin has a higher side-effect burden than many NSAIDs; GI and CNS effects are common.
Serious adverse events include GI bleeding, renal impairment, and rare seizures in neonates.
2 documented effects
Not specified
Take with food; consider gastroprotective agent for chronic use.
Monitor for symptom escalation or new adverse effects.
Not specified
Stop drug and seek urgent evaluation.
Monitor for symptom escalation or new adverse effects.
2 documented effects
Not specified
Monitor; dose at bedtime if tolerated.
Monitor for symptom escalation or new adverse effects.
Not specified
Monitor neonates closely and discontinue if seizures occur.
Monitor for symptom escalation or new adverse effects.
1 documented effect
Not specified
Assess renal function and discontinue if significant decline noted.
Monitor for symptom escalation or new adverse effects.
For babies taking Indomethacin, watch for signs of side effects. This medication is generally well-tolerated in infants when used as directed.
If your toddler is taking Indomethacin, they might feel different. This is usually temporary and normal.
Take this medicine with food and tell us if your tummy hurts or you feel dizzy.
Report headaches, stomach pain, or less urine right away.
A: Take with meals and monitor for bleeding.
When to validate: Seek care for black stools or vomiting blood.
A: Rest and avoid operating machinery; report persistent symptoms.
When to validate: Call if dizziness interferes with daily life.
Clinical assessment framework for Indomethacin adverse effects using standardized severity grading.
Parent and clinician concerns about Indomethacin