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Peds Calc

Safety Information

Loratadine Contraindications & InteractionsWhen Not to Use & Important Drug Interactions

Understanding when Loratadine should not be used and what medications it interacts with is essential for safe pediatric care.

Back to Loratadine Overview

Contraindications

  • Known hypersensitivity to loratadine or desloratadine

Use With Caution

  • Significant hepatic impairment (use caution or adjust)
  • Renal impairment (use caution)
  • Concomitant CNS depressants if drowsiness occurs (use care)
  • Phenylketonuria (PKU): some chewables/solutions may contain aspartame—check product

Pregnancy & Lactation

Discuss with a clinician; in breastfeeding, non‑sedating antihistamines are generally preferred—seek individualized advice.