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Peds Calc

Scientific Understanding

How Nitrofurantoin WorksMechanism of Action in Children

Nitrofurantoin is reduced by bacterial flavoproteins into reactive intermediates that damage DNA, ribosomal proteins, and metabolic enzymes within urinary pathogens.

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Understanding How Nitrofurantoin Helps Your Child

Nitrofurantoin is reduced by bacterial flavoproteins into reactive intermediates that damage ribosomal proteins, DNA, and metabolic enzymes, leading to rapid bacterial death in the urinary tract.

Molecular Targets & Receptors

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Journey Through the Body

Absorption

Bioavailability

Not specified

Time to Peak

Not specified

Food Effect

Not specified

Route

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Elimination

Half-life

Not specified

Primary Route

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Scientific References

Nitrofurantoin Pharmacologyโ€ขClinical Microbiology Reviews (2019)review