Pediatric Drug Interactions with Ondansetron

• Apomorphine: contraindicated (risk of profound hypotension)
• QT‑prolonging agents (e.g., certain macrolides, fluoroquinolones): additive risk—use caution
• Electrolyte abnormalities (low K+/Mg2+): increase QT risk—correct before use
• Serotonergic combinations (SSRIs/SNRIs/MAOIs/triptans): rare serotonin syndrome—monitor clinically