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Peds Calc

Safety Information

Oseltamivir Contraindications & InteractionsWhen Not to Use & Important Drug Interactions

Understanding when Oseltamivir should not be used and what medications it interacts with is essential for safe pediatric care.

Back to Oseltamivir Overview

Contraindications

  • Known hypersensitivity to oseltamivir or formulation components

Use With Caution

  • Significant renal impairment (dose adjustment required)
  • Hereditary fructose intolerance (sorbitol in some suspensions)
  • History of severe nausea/vomiting with antivirals (give with food, monitor)
  • Concomitant live attenuated influenza vaccine (LAIV) within the past 48 hours or planned soon (antivirals may reduce LAIV effectiveness)

Pregnancy & Lactation

Discuss risks/benefits with a clinician; pediatric dosing is for the child, but considerations apply for breastfeeding parents handling dosing and illness in the household.