Penicillin VK is generally well tolerated in children. Most side effects are mild and self‑limited. Serious allergic reactions are uncommon but require immediate care.
nausea, abdominal discomfort, or diarrhea — giving with a small snack may help.
delayed, non‑urticarial rashes can occur and are not always a true allergy; seek care for hives, swelling, or breathing trouble.
diaper dermatitis or oral thrush may occur; treat if symptomatic.
immediate hypersensitivity (hives, wheeze, anaphylaxis) — call emergency services.
Typical effects include mild GI upset and transient rash. Educate families on warning signs of true allergy.
2 documented effects
Small snack, hydration
Fluids; seek care if severe or bloody
2 documented effects
Supportive; distinguish from urticaria
Discontinue and seek urgent care
1 documented effect
Evaluate if bruising/fatigue present
Parent and clinician concerns about Penicillin VK