Review infection status, vaccine timing, and comorbidities before prednisolone.
Absolute: hypersensitivity, untreated systemic fungal infection. Relative: serious/untreated infections, varicella/measles exposure, significant immunosuppression, uncontrolled diabetes, severe hypertension/CV disease, PUD, ocular HSV, glaucoma/cataracts, osteoporosis risk.
Avoid unless concurrent antifungal therapy and specialist care
Why: Immunosuppression can worsen invasive fungal disease
Urgent discussion about prophylaxis and timing of steroids
Monitor glucose and adjust sick‑day plan
Discuss risks/benefits with a clinician; systemic steroids can be used when benefits outweigh risks. For breastfeeding parents, brief courses are generally compatible—seek individualized guidance.