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Peds Calc

Propranolol Pediatric Dosing Calculator

Calculate pediatric dosages for Propranolol in seconds with our Propranolol pediatric dosing calculator. Input the details, press Calculate Dosage, and get precise Propranolol prescriptions for every child!

Enter the weight of the baby in lbs

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Select the strength of Propranolol

Adjust the slider to set the frequency (times per day).

Select the desired frequency (times per day).

Select the desired to set the dosage amount.

By using the "Calculate Dose" button on pedscalc.com, you acknowledge and agree that while our calculations aim for accuracy, final prescription responsibility lies solely with you, the healthcare provider. pedscalc.com and its operators are not liable for any errors or omissions, or for the results obtained from the use of this information. Always verify calculations and exercise professional judgment.

About Propranolol

Propranolol is a non-selective beta blocker used for pediatric arrhythmias, migraines, hyperthyroidism symptoms, and infantile hemangioma.

Propranolol in Pediatrics

Assess baseline heart rate, blood pressure, and blood glucose (in infants) prior to initiation; titrate every 3–7 days while monitoring vitals.

Screen for reactive airway disease—beta-2 blockade can precipitate bronchospasm; consider cardioselective alternatives when asthma is uncontrolled.

Give with feeds in infants receiving Hemangeol to reduce hypoglycemia risk and counsel caregivers to hold doses during poor intake or vomiting.

For arrhythmia prophylaxis, coordinate with cardiology to adjust dosing around procedures and monitor QTc for concurrent antiarrhythmics.

Avoid abrupt withdrawal; taper over 1–2 weeks to prevent rebound tachycardia and hypertension.

Monitor for sleep disturbances, mood changes, or exercise intolerance in school-aged children and adolescents on chronic therapy.

Propranolol Indications & Uses in Pediatrics

Propranolol offers broad autonomic modulation in pediatrics.

Used for arrhythmia, hemangioma, migraine, and hyperthyroid symptoms.

ConditionAge RangeFirst Line?Notes
Infantile hemangioma requiring systemic therapyInfants ≥5 weeks postmenstrual ageYesInitiate under specialist supervision with monitoring for hypoglycemia, bradycardia, and blood pressure changes. Continue for at least 6 months and reassess skin findings every 1–2 months.
Supraventricular tachycardia prophylaxisInfants, children, and adolescentsYesUse for rate control or to prevent recurrent SVT episodes when ablation is deferred. Adjust dosing based on weight and heart rate response.
Migraine preventionAdolescentsYesDaily dosing reduces migraine frequency; reassess every 6 months for continued need and taper slowly when discontinuing.
Symptomatic hyperthyroidismChildren and adolescentsYesProvides rapid heart rate and tremor control while antithyroid therapy takes effect; dose adjustments mirror thyroid status changes.

Common Pediatric Side Effects from Propranolol

Propranolol side effects stem from beta blockade and include bradycardia, hypotension, and hypoglycemia in infants.

Monitor vitals and glucose especially during initiation and illness.

Cardiovascular System

Bradycardia

Commonmoderate

Hypotension

Uncommonmoderate

Metabolic System

Hypoglycemia (infants)

Uncommonserious

Respiratory System

Bronchospasm

Rareserious

Neurologic System

Fatigue/drowsiness

Commonmild

Key Safety Information

Most Common Side Effects:
  • Mild stomach upset
  • Temporary drowsiness
  • Minor skin reactions
When to Call Your Doctor:
  • Severe allergic reaction
  • Persistent symptoms
  • Unusual bleeding

Propranolol Pediatric Administration & Instructions

Administration guidance for propranolol therapy.

Give at the same times each day with or without food, but stay consistent. For liquid, use the supplied syringe. Avoid abrupt discontinuation without clinician guidance.

Monitor heart rate and blood pressure at home if directed. For infants receiving hemangioma therapy, give doses during daytime after feeding to reduce hypoglycemia risk.

Emergency contact: Seek urgent care for trouble breathing, fainting, very slow heart rate, or signs of low blood sugar (sweating, irritability, lethargy).

Inform all healthcare providers that your child takes propranolol before procedures or new medications.

Propranolol Contraindications & Warnings in Pediatrics

  • History of severe bronchospasm or asthma precipitated by beta-blockers: Nonselective beta blockade can provoke life-threatening bronchoconstriction; reserve therapy for alternative agents in reactive airway disease.
  • Marked bradycardia, sick sinus syndrome, or second/third-degree AV block without a pacemaker: Propranolol slows AV nodal conduction and can precipitate symptomatic heart block in susceptible patients.
  • Cardiogenic shock or overt decompensated heart failure: Negative inotropic effects worsen low-output states; stabilise circulation before considering beta-blockade.

How Propranolol Works - Mechanism of Action

In hemangiomas, propranolol induces vasoconstriction, inhibits angiogenic signals, and promotes apoptosis of capillary endothelial cells.

Propranolol reduces adrenergic signaling through beta blockade.

Propranolol Clinical Pearls & Expert Tips

Propranolol pearls for pediatric cardiology and dermatology teams.

Highlight monitoring and safety considerations.

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Illness protocol

Instruct caregivers to hold doses and call for vomiting, poor intake, or respiratory illness in infants.

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Vitals monitoring

Check heart rate and blood pressure at initiation, dose changes, and routine follow-up.

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Taper plan

Plan a gradual taper over 1-2 weeks when discontinuing to avoid rebound tachycardia.

Quality Score: 7/10
0 Evidence Sources
0 Practice Updates

Parent & Caregiver Resources for Propranolol

Resources for Parents & Caregivers

Understanding your child's medication is important. We've created comprehensive guides to help you safely administer Propranolol and monitor your child's response to treatment.

Frequently Asked Questions

Hold propranolol and contact your clinician. Illness with poor intake increases risk of low blood sugar, especially in infants, so the medicine should be paused until appetite returns.

Yes. Vivid dreams, nightmares, or insomnia can develop because propranolol crosses the blood-brain barrier. Report persistent sleep problems so dosing time or therapy can be adjusted.

Yes. Never stop beta blockers abruptly. Follow the clinician’s taper instructions (usually 1–2 week reduction) to prevent rebound tachycardia and hypertension.

Nonselective beta blockers can worsen bronchospasm. Inform your clinician if your child has asthma or develops new wheezing—the dose may be lowered or switched to a different medication.