Sucralfate forms an aluminum salt complex that adheres to ulcerated mucosa. Review renal function and drug separation logistics before prescribing.
Absolute contraindication is hypersensitivity to sucralfate or aluminum-containing compounds. Relative contraindications include chronic kidney disease, significant constipation, prematurity, and situations where spacing other critical medications is impractical.
Rare but reported; switch to an alternative mucosal protectant.
Aluminum-containing complex may accumulate; monitor aluminum levels and avoid prolonged use.
Cumulative exposure increases risk of encephalopathy and osteomalacia.
Sucralfate's binding effect can worsen ileus; maintain an appropriate bowel regimen.
Viscous suspension may clog feeding tubes; flush thoroughly and monitor residuals.