Terbinafine is an allylamine antifungal that is fungicidal for dermatophytes by collapsing ergosterol synthesis.
Terbinafine inhibits squalene epoxidase, a key enzyme in fungal ergosterol synthesis. Accumulation of toxic squalene leads to fungal cell death, making terbinafine fungicidal against dermatophytes.
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Food Effect
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Primary Route
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