For children 1 year and older, the oseltamivir dose is set by weight: 30 mg for 15 kg or less, 45 mg for over 15 to 23 kg, 60 mg for over 23 to 40 kg and 75 mg over 40 kg, twice daily for treatment or once daily for prevention. The chart below gives the mL of 6 mg/mL liquid and the infant checks.
These common bands show the mg amount per dose. Use the schedule table below to decide whether that dose is given twice daily for treatment or once daily for prevention.
| Weight band | mg per dose | 6 mg/mL liquid | Capsule handoff |
|---|---|---|---|
| <=15 kg | 30 mg | 5 mL | 30 mg capsule if prescribed and swallowed safely |
| >15-23 kg | 45 mg | 7.5 mL | 45 mg capsule |
| >23-40 kg | 60 mg | 10 mL | Usually two 30 mg capsules if capsules are used |
| >40 kg | 75 mg | 12.5 mL | 75 mg capsule |
The same weight-band mg amount can be used in different ways. Confirm whether the plan is treating influenza or preventing influenza after a selected exposure before measuring the dose.
| Scenario | Typical frequency | Typical duration | Check first |
|---|---|---|---|
| Influenza treatment | Twice daily | 5 days | Best started as early as possible, especially within the first 48 hours when appropriate. |
| Post-exposure prophylaxis | Once daily | 7 days after the last known exposure (CDC); the FDA label says 10 days after close contact for ages 1 to 12 and at least 10 days from age 13. Confirm which one your clinician uses. | Not for every exposure. Risk factors, timing, and local guidance matter. |
| Age group | Treatment check | Prevention check | Why it matters |
|---|---|---|---|
| Premature infant | Do not use the term-infant 3 mg/kg or band dosing; CDC doses by postmenstrual age | Specialist/pathway dosing only | CDC doses premature infants by postmenstrual age because clearance is lower. |
| Term infant under 3 months | 3 mg/kg per dose twice daily for 5 days (CDC) | Not recommended unless the situation is judged critical (CDC) | The FDA label covers treatment from 2 weeks of age; CDC and AAP also recommend it for younger infants. |
| 3 months to under 1 year | 3 mg/kg per dose twice daily for 5 days (CDC, FDA label) | 3 mg/kg per dose once daily (CDC; off-label, as the FDA label covers prevention from 1 year) | AAP suggests 3.5 mg/kg twice daily at 9 to 11 months; CDC says a benefit of the higher dose is unknown. |
| 1 year and older | Use weight-band mg dose twice daily when treatment is indicated | Use weight-band mg dose once daily when prevention is indicated | Then convert to 6 mg/mL liquid or capsule strength. |
The common suspension is 6 mg/mL. Once the mg dose and schedule are confirmed, liquid conversion is simple: divide the mg dose by 6.
mL per dose = mg per dose / 6
Example: 45 mg / 6 mg/mL = 7.5 mL per dose.
| Form | Best fit | Check |
|---|---|---|
| 6 mg/mL suspension | Younger children, anyone who cannot swallow capsules, or doses that need mL measurement. | Shake well, use an oral syringe, and verify the bottle concentration before measuring. |
| 30 mg capsule | The <=15 kg band when a capsule is prescribed, or part of a 60 mg dose. | Capsule contents may be mixed only when the product plan supports it. |
| 45 mg capsule | The >15-23 kg band when capsules are appropriate. | Do not substitute a 75 mg capsule for a lower band. |
| 75 mg capsule | The >40 kg band or adult-size pediatric/adolescent plan. | Confirm treatment versus prophylaxis frequency before giving repeat doses. |
For children 1 year and older, common bands are 30 mg for 15 kg or less, 45 mg for over 15-23 kg, 60 mg for over 23-40 kg, and 75 mg for over 40 kg. Confirm the indication and local pathway.
For 6 mg/mL suspension, 30 mg is 5 mL, 45 mg is 7.5 mL, 60 mg is 10 mL, and 75 mg is 12.5 mL.
The weight-band mg amount is often the same, but the schedule is not. Treatment is usually twice daily for 5 days, while prophylaxis is usually once daily for a different duration.
Term infants under 1 year get 3 mg/kg per dose twice daily for treatment (CDC), not the band table. For prevention, CDC uses 3 mg/kg once daily from 3 months and does not recommend it under 3 months unless the situation is critical. Premature infants need special dosing because medication clearance differs.
The biggest benefit is when treatment starts early, but clinicians may still treat selected high-risk, hospitalized, or severe cases later. Follow the clinician plan.